Clinical Application of the Ratio of Acceleration Time to Ejection Time in the Diagnosis of Native Valve Low-Flow, Low-Gradient Severe Aortic Stenosis - Abstract
Severe aortic stenosis is defined based on the echocardiographic parameters including peak velocity, mean pressure gradient across the aortic valve and aortic valve area.
Grading of AS solely based on these parameters may give discordant results and raise uncertainty about the true AS severity particularly in scenarios like less severe AS, low flow
across the aortic valve due to reduced LVEF and presence of small aortic root. Low dose DSE has been validated to differentiate true versus pseudo severe AS. AVAproj can be utilized
when low dose DSE is non-conclusive. The aim of this study is to evaluate the relationship between AT/ET and calculated AVAproj in patients with LFLG severe AS with reduced EF to
determine a cutoff for this ratio to identify true severe AS in these patients.