Tuberculosis is a public health problem for many countries. Extra nodal ENT locations are rare and may be localized in cervical lymph nodes, pharyngeal, laryngeal, nasal, buccal cavity and glandular sites parotid, submandibular and thyroid glands. This study reports 25 cases of extra pulmonary tuberculosis colliged in our department (lymphatic tuberculosis exclude). The results showed many and variable localizations: pharyngeal, laryngeal, otitis, nasal and paranasal, thyroid gland and 3 cases of multiples localizations. The diagnosis was difficult and requires clinical exam, biology and imaging procedure. The final diagnosis of tuberculosis was made after bacteriologic or histopathologic exam of different materiel (biopsy or after surgical procedure). All patients received antituberculous therapy with a favorable outcome.