Myeloid Sarcoma (MS) is a rare condition where leukemic cells proliferate independently, often alongside or during relapse of related blood cancers such as Acute Myeloid Leukemia (AML), and other leukemias. MS typically manifests as tumors of immature myeloid cells in various body sites. Skin involvement shows a single, solid tumor with rapid growth, commonly on the face, scalp, or trunk. While primarily seen in these areas, MS can appear in any organ. Some cases exhibit multiple or widespread lesions. We describe the case of a 44-year-old female patient whose laboratory tests, extension studies, skin biopsy, and immunostaining align with the diagnosis of rapidly advancing and poor prognosis Myeloid Sarcoma.