The Effectiveness of Selective Serotonin Reuptake Inhibitors for Prevention of Vestibular Migraine and its Effect on the Quality of Life - Abstract
Objective: This study aimed to evaluate the effect of citalopram treatment in patients with Vestibular Migraine.
Method: Three hundred and four patients with VM included in the study. 152 patients were treated with Citalopram, and 152 patients were treated with
Amitriptyline for six months. Scores of Dizziness Handicap Inventory (DHI) questionnaire and number of vertigo attacks were compared for two groups.
Results: After treatment, the DHI scores decreased from 52,26±20,19 to 12,29±8,93 and from 55,12±9,58 to 24,02±9,45 (p<0,001), the number of
vertiginous attacks decreased from 4 to 0,4 and from 4 to 1 (p<0,001) in Citalopram and Amitriptyline groups, respectively.
Conclusion: According to our findings, citalopram treatment decreases the frequency and severity of attacks and increases VM patients’ quality of life