Sleep Disorders in Inflammatory Bowel Disease - A Mini-Review - Abstract
Inflammatory bowel diseases, consisting of Crohn’s Disease, Ulcerative Colitis, and IBD unclassified are chronic autoimmune conditions characterized by gastrointestinal inflammation that also can affect other organ systems. When evaluating patients with inflammatory bowel disease, screening for extra-intestinal manifestations is essential. An underappreciated extraintestinal manifestation of inflammatory bowel disease is sleep disturbance. The purpose of this review is to summarize the existing and evolving literature linking inflammatory bowel disease with sleep disorders. Sleep Disorders in inflammatory bowel disease may stem from the disease process itself, the symptoms of the disease, or side effects of treatments. For example, disordered sleep may be secondary to pain, bowel changes, concomitant mood disorders, or to glucocorticoid use. We will also investigate how the disease process may affect sleep directly. When in the state of an active flare of inflammatory bowel disease, patients have increased difficulties with sleep, particularly in Crohn’s disease. Further research may lead to advances in therapeutic options for sleep disorders in this patient population.