Background: The aim of this study was to analyze the feasibility and effectiveness of laparoscopic treatment of upper urinary tract stones through the experience of urology department B. Methods: We retrospectively and monocentrically selected patients who underwent laparoscopic treatment of upper urinary tract stones from January 2016 to December 2020. The collection was carried out on archived files. The endpoint was the occurrence of complications, the duration of the operation, the rate of SF and the length of hospitalization. Results: A total of 33 patients were included in our series. The average age of our patients was 53 years old. There is a male predominance: 13 female patients (39.6%) for 20 male patients (60.4%). During the study period, 33 interventions involving the treatment of upper urinary tract stones were performed in our department, which is divided into 16 (48.5%) ureterotomy, 3 (9.1%) nephrotomy, 13 (39.4%) pyelotomy and 1 (3%) ureterotomy and pyelotomy. In our series, the mean operative time was 118.2 min. Estimated blood loss averaged 100ml with extremes of a few milliliters to 130ml. Intraoperative complications were reported in 2 (6.1%) patients, a conversion was necessary in 6 cases (18.2%). The postoperative period was simple in 28 (84.8%) patients with an average hospital stay of 4.8 ± 2.2 days with extremes of (2-15 days). It’s estimated that resuming normal physical activity takes an average of 3 weeks. The postoperative complication rate according to Clavien-Dindo was 15.1%. The rate of SF (Stone-free) in our series was 91%. Conclusions: With a high SFR rate of up to 91% and a low complication rate, laparoscopic ureterotomy and pyelotomy are safe techniques that provide rapid recovery and may be the first treatment option for patients with large stones. Ureters, as well as for those with a history of primary treatment failure.