Determination of Immune Response of Cevac New L® (La Sota Strain) Vaccine in Pigeon - Abstract
Newcastle disease is a devastating poultry disease all over the world including Bangladesh. The present study was conducted to investigate the immune response of ND live vaccines Cevac New L® (La Sota strain) in pigeons during the period from January, 2014 to June, 2014. For the purposes of this experiment 40 pigeons were divided into 2 groups. In group A (n=20) and B (n=20,unvaccinated control) vaccination was performed twice with Cevac New L® at day 5 and 21 of age i/o. Serum antibody titre was evaluated by the means of hemagglutination inhibition test (HI). The Mean±SD of HI titre (log2X) of group A was 4.75±0.64, 5.65±0.59, 6.85±0.67, 7.55±0.51,6.35±0.67, 5.20±0.77 at day12, 19, 28, 35, 42 and 49 of post vaccination respectively. It was observed that serum Ab level was gradually increased from day 12 to day 35 and declined slowly after day 42 in group, leading to good protection to the pigeon against ND. There was a significant (p<0.05) differences between the HI titre of group A and B. From the result, it was revealed that Cevac New L® (La Sota Strain) produced better immune response in the pigeon body against ND in respect of HI Abtitres response.