Staphylococcus aureus Resistance against Methicillin in Pets: a Review - Abstract
Present review was carried out in order to explore the geographical distribution, prevalence and resistance mechanism of Staphylococcus aureus against methicillin worldwide. Study indicated that Staphylococcus aureus infections in pets are a common problem worldwide. Countries where antibiotics like methicillin is frequently misused, resistance has developed in the host. Resultantly antimicrobial therapy fails. Further, Staphylococcus aureus resistant to methicillin (SARM) possess a gene mec-A which play key role in the resistance mechanism. These genes have code sequencing
GAT GAA ATG ACT GAA CGTCCG ATTA and CAA ATT CCA CATTGT TTC GGT CTAA. However, using PCR this organism can easily detected. The mecA gene is responsible for resistance to methicillin and encoding the low-affinity penicillin binding protein (PBP 2). Researchers also reported that dogs are more infected with Methicillin Resistant Staphylococcus aureus (MRSA) compared to cats. Human can significantly be infected when by contact with MRSA infected pet. In conclusion, MRSA is a common threat to the pets including cats and dogs throughout the globe and antibiotics misuse is the major reason for that.