Overview on Emorfazone and Other Related 3(2H) Pyridazinone Analogues Displaying Analgesic and Anti-Inflammatory Activity - Abstract
A series of structurally varied derivatives of 3(2H)-pyridazinone were tested for their analgesic and anti-inflammatory activity by using different test models. The analgesic and anti-inflammatory activity of the compounds were found to be significant as compare with reference drugs. Some of the 3(2H)-pyridazinone derivatives are having analgesic and anti-inflammatory activities. Pyridazine derivatives, Emorfazone is a non-steroidal analgesic anti-inflammatory drug which is clinically used for ailments such as pain, inflammation and rheumatoid arthritis. Various pyridazine derivatives also exhibited non-steroidal analgesic anti-inflammatory activity.