Recent Articles
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May 30, 2016 Short CommunicationAbstract While Mentha x piperita L. is a popular herb used in the northern region of Portugal to prepare tisanes the information about its possible toxicity is scarce. This Study was designed to assess the toxicity of the aqueous extract on the physiology, mo.....
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September 02, 2015 Research ArticleAbstract The current study reports design and diversity oriented synthesis of novel heterocycles incorporating of thioureido linkage on position no C-4 which not yet been explored and could find new applications in biology. Employing reagent based skeletal di.....
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September 02, 2015 Research ArticleAbstract Introduction: Cathepsin K is being targeted for the treatment of various human disease including osteoporosis and cancer. In the present study, a compound, which contains a 2-cyanopyrimidine scaffold with optimal substituents that can interact with S.....
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May 28, 2015 Review ArticleAbstract Transition-metal complexes have shown significant anti-tumour potential and have advanced towards clinical trials. However, tumour cells often develop resistance to chemotherapeutics, which couple to the inherent compound’s’ toxicity and solubil.....
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April 23, 2015 Review ArticleAbstract Complementary and alternative medicine involves the use of herbs and medicinal plants as an alternative to mainstream western medical treatment. A large number of Indian medicinal plants have been reported to possess immunostimulant activity and thus.....
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April 02, 2015 Review ArticleAbstract Urea transporter (UT) proteins, including isoforms of UT-A in kidney tubule epithelia and UT-B in vasa recta endothelia and erythrocytes, play an important role in the urine concentration mechanism by mediated an intra renal urea recycling, suggesti.....
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March 12, 2015 Research ArticleAbstract The 3-brominated pyrroldione 1a served as starting material for the preparation of a series of substituted N-methyl 3-amino-pyrrol-2,5-diones, using a Cu catalysed substitution reaction. Initially the newly synthesised compounds were tested at a high.....
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February 10, 2015 Review ArticleAbstract Human stem cells have a major effect in the development of human bodies. Acting as an in vitro model, human stem cells have a great value in the study of the mechanism of individual development and in the cell replacement and regeneration treatment.....
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February 02, 2015 Short CommunicationAbstract The aim of this present article is to underscore the recent evidence linking anticancer activity and free radical scavenging activity of mycotoxins and its significance in the development of newer anticancer drugs. Although acute exposure to a massi.....
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January 14, 2015 Review ArticleAbstract A series of structurally varied derivatives of 3(2H)-pyridazinone were tested for their analgesic and anti-inflammatory activity by using different test models. The analgesic and anti-inflammatory activity of the compounds were found to be significan.....
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November 25, 2014 Review ArticleAbstract The prokaryotic type II topoisomerases (DNA gyrase and topoisomerase IV) and the eukaryotic type II topoisomerases represent the cellular targets for quinolone antibacterial agents and a wide variety of anticancer drugs, respectively. In view of the .....
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November 12, 2014 Editorial