Resistant Hypertension in Thoracoabdominal Aortic Dissection Involving the Renal Arteries - Abstract
There is little longitudinal BP data in patients with thoracoabdominal aortic dissections (TAAD). In patients attending an aortic diseases clinic, thoracic aortic dissection (TAD) having false lumen extensions past the renal arteries (Group 1) were compared to TAD without renal artery involvement (Group 2). Resistant hypertension (rHTN) was present in 28.6% of Group 1, significantly (p=0.038) greater than the 4.8% in Group 2. Group 1 had a significantly (p=0.04) greater prevalence of coronary artery disease. BP’s post-TAD were not significantly different between the two groups likely due to the greater number of antihypertensive drugs used in rHTN. There was a higher proportion of ARB usage in Group 1. TAAD, with the right renal artery supplied by the false lumen and the left renal artery supplied by a true lumen had the greatest prevalence (42.9%) of rHTN; significantly (p<0.05) greater than other types of renal artery dissections. The data suggest, rHTN is prevalent in TAAA, necessitating vigorous treatment but good BP control is possible. The nature of the renal artery involvement identifies potential rHTN.