Genome Editing in Human Pluripotent Stem Cells: A Multidisciplinary Approach to Dissecting Cellular Mechanism of Cardiomyopathy - Abstract
Rapid advances in genome editing technology allow the targeted genes to be modified both in vitro and in vivo. In this short communication, we will summarize the development and progress in genome editing techniques and highlight their application in human induced pluripotent stem cells, which have been utilized to investigate the pathophysiological mechanisms of gene mutation - induced cardiomyopathy.