Strategies in Developing Fluorescent Probes for Live Cell Imaging and Quantitation of Hydrogen Sulfide - Abstract
The involvement of hydrogen sulfide (H2S) in a number of cellular signal transduction pathways has triggered great interest in the development of selective and sensitive detection methods for H2S. This mini-review summarizes three current strategies used in the design of hydrogen sulfide-reactive fluorescent probes, including copper complexation, redox reaction, and nucleophilic cyclization. Examples from these three categories of fluorescent probes are also compared and discussed briefly.