Bioprocess optimization for highly lipophilic biomolecules is frequently constrained by mass transport resistances across aqueous-organic interfaces. This study details the engineering and kinetic modeling of a nano-vectorized lipid-matrix carrier designed to enhance the interfacial mass transfer of hydrophobic molecular signals across cellular bilayers. Utilizing a structurally calibrated monounsaturated fatty acid vehicle, we mathematically characterize the reduction of interfacial tension and the corresponding changes in membrane permeation flux (J). Computational transport simulations and steady-state mass balance equations indicate that optimizing carrier lipophilicity yields a non-linear acceleration in absorption velocity, achieving a steady-state flux efficiency threshold of 92% compared to less than 20% for conventional unvectorized crystalline suspensions. By preventing local mass accumulation and maintaining thermodynamic equilibrium at the epithelial boundary, this transport architecture provides a scalable framework for fluidic flow control and predictive membrane maintenance in complex biological systems.