Natural Compounds as Therapeutic Agents to Treat Cystic Fibrosis - Abstract
Despite being identified as a unique disease almost 100 years ago, drugs aimed
at treating the basic defect in cystic fibrosis (CF) have only recently been approved
for clinical use. Marketed as Kalydeco and Orkambi (Vertex Pharmaceuticals), these
medications have improved the lives of many CF patients; yet the goal of treating
all CF patients remains to be achieved. Although effective, concern has been raised
regarding the annual cost of treating patients with these drugs, especially since
patients will be prescribed such medications for life. The current move to a more holistic
approach to medical care has prompted many people to try various herbal or “natural”
remedies. In this review, was assess three such natural treatments; genistein, curcumin
and resveratrol, and evaluate their potential as adjunct therapies for patients with CF.