Volume 12 - Issue 1 Articles
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ArticleSeptember 10, 2025 | Pages : 205 - 450Abstract Object: Immunotherapy targeting PD-1 and CTLA-4 have made breakthrough in cancer treatment. However, the Cases of Colorectal Cancer (CRC) with Microsatellite Stable (MSS) do not respond to the dual therapy. Thus, new strategy will be needed to ove.....
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ArticleJune 25, 2025 | Pages : 205 - 450Abstract Background: As a common and lethal malignancy, gastric cancer remains in urgent need of investigation of its molecular mechanisms and effective molecular targets for therapy to improve patient outcomes. MRPL3, a mitochondrial ribosomal protein, pla.....
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ArticleMarch 03, 2025 | Pages : 205 - 450Abstract This paper presents a case of twin brothers afflicted with Crohn’s Disease (CD), characterized by a rare missense mutation c.-12+198G>T in the interferon regulatory factor 5 (IRF5) gene, which is extremely uncommon in the Chinese population and .....
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ArticleFebruary 27, 2025 | Pages : 205 - 450Abstract Objective: Quality of life is of great importance in chronic diseases such as ulcerative colitis. The aim of this study was to assess the correlation between quality of life and disease activity. Material and Method: In this study, we included pa.....
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