New Horizons in Cystic Fibrosis - A Review - Abstract
Cystic fibrosis (CF) is the most common life-limiting autosomal recessive disease
among Caucasians. Remarkable advances in our understanding of the pathophysiology,
diagnosis and treatment of CF have been made since the discovery of CFTR gene. Care
of cystic fibrosis patients is complex and requires a team approach. Recent advances,
novel treatments and the multidisciplinary team approach have improved survival
in CF, transforming it into a predominantly adult disease. This review highlights the
pathogenesis of cystic fibrosis and summarizes diagnosis, clinical manifestations and
treatment guidelines.