Diagnosis and Treatment of Parathyroid Carcinoma: Report of Seven Cases and Review of Literature - Abstract
Objective: To discuss the clinical features, diagnosis and treatment of parathyroid carcinoma.
Methods: From January 2005 to December 2014, a total of 7 patients were recruited. Their clinical data, clinical manifestation, examinations and surgical modes were analyzed retrospectively.
Results: One 70-year old patient died after operation because of severe hypocalcaemia. The remaining 6 patients were followed up for 37 + 20.0 months (16-72) months. 2 patients underwent En bloc resection and 1 patients underwent parathyroidectomy were followed up until now without recurrence or metastasis. 3 patients underwent parathyroidectomy appeared metastasis or recurrence in the follow-up.
Conclusion: Our experience with small numbers indicated that En bloc resection in initial operation can reduce recurrence and metastasis rate. Aggressive treatment should be considered in initial operation. It can improve the cure rate.