p53 is a tumor suppressor gene and it has been mapped to chromosome 17.Under stress, p53 levels rises in the cell and leads to cell cycle arrest in G1 phase. Long noncoding RNAs (lncRNAs) are relatively abundant component of mammalian transcriptome. There are many Long noncoding RNA which are regulated by p53. In this review we have discussed some of the lncRNAs which are related to p53 such as MALAT1, NEATI, LOC285194, LOC401317, PANDA, lincRNA-p21, LincRNA-ROR, lincRNA H19, MEG3 and PURPL. It is very difficult to discriminate between lncRNAs and mRNA. But there are some criteria which can be used to discriminate between protein coding genes and lncRNAs such as lncRNA genes are shorter and have fewer number of exons. Exon in lncRNAs are shorter than protein coding genes. Protein coding genes have protein coding domains as demonstrated by pfam.