Recent Articles
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December 01, 2024 Research ArticleAbstract Chemotherapy induces Myeloid-Derived Suppressor Cells (MDSCs) to be the primary negative regulator of immunity in the Tumor Microenvironment (TME). MDSCs inhibit cellular immune responses by enhancing tumor immune escape, severely endangering human.....
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December 01, 2024 Research ArticleAbstract A study was carried out to estimate the gross alpha and beta radionuclide activity in groundwater sources within Mubi North metropolis, Adamawa State. Five water samples were collected from residential areas and analyzed using the Protean Instrumen.....
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December 01, 2024 Review ArticleAbstract The weed resistance has become the major factor restricting crop production, and the mechanism of weed resistance is divided into target resistance (TSR) and nontarget resistance (NTSR). Target resistance includes target gene mutation and target .....
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July 25, 2024 Case ReportAbstract Given neoadjuvant therapy has potential to increase overall survival before oesophagectomy, neoadjuvant chemotherapy or chemoradiotherapy are recommended before the curative surgery for patients with resectable locally advanced esophageal cancer(LAEC.....
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July 31, 2024 Review ArticleAbstract FOXM1 is an oncogenic transcription factor that promotes tumor growth, metastasis, and progression of drug resistance, and its high expression correlates with poor patient survival across various solid tumors. Mutations in the p53 tumor suppresso.....
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June 16, 2024 Research ArticleAbstract Laryngeal squamous cell carcinoma (LSCC) evolves from normal tissues through precancerous conditions, ultimately culminating in primary laryngeal squamous cell carcinoma. To elucidate the heterogeneity of tumor cells and their interactions during thi.....
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June 16, 2024 Review ArticleAbstract Chimeric antigen receptor (CAR) myeloid cells are a promising potential alternative to CAR T-cells for solid tumor therapies. Myeloid CAR therapies have been tested in preclinical studies by either transferring established CD3-based T-cell CARs into .....
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June 16, 2024 Review ArticleAbstract Adoptive immune cell therapy (ACT) utilizes a patient’s own immune cells to target and eliminate cancer cells. This article explores the application of various cell types in ACT, including T cells, NK cells, macrophages, and dendritic cells. Each.....
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February 29, 2024 Research ArticleAbstract A potent stimulation of fibroblast collagen production is one of the crucial pleotropic effects of transforming growth factor ? (TGF-?) and has been considered to play a crucial role in the pathogenesis of fibrotic diseases including Systemic Scleros.....
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February 29, 2024 Review ArticleAbstract The examination of the prostate biopsy procedure is essential in the optimization of the diagnostic pathway of such a prevalent affliction as prostate cancer among men worldwide. With the core needle biopsy being the standard of care for the diagnosi.....