Breaking Barriers to Heart Health: Harnessing the Power of Natural Products and Lifestyle Interventions in Combating Cardiovascular Disease - Abstract
Cardiovascular diseases (CVD) are the leading cause of mortality and morbidity worldwide, significantly contributing to the global burden of disease. CVD encompasses disorders of the heart and blood vessels, including coronary heart disease, heart failure, arrhythmia, myocardial infarction, and hypertension. While traditional risk factors such as genetics, hypertension, and hyperlipidemia are crucial, unhealthy lifestyle choices-including diets high in refined carbohydrates, fats, and salt, physical inactivity, smoking, excessive alcohol consumption, stress, and poor sleep habits-are major modifiable contributors to CVD. These factors promote conditions like atherosclerosis, where fatty deposits accumulate on arterial walls, restricting blood flow and causing serious cardiovascular complications. This review examines the impact of lifestyle interventions-dietary modifications, physical activity, smoking cessation, and stress management-on cardiovascular health and their integration into routine practice. Heart-healthy diets like the Mediterranean and DASH patterns effectively reduce blood pressure, improve lipid profiles, and mitigate inflammation. Regular physical activity strengthens the heart, improves endothelial function, reduces arterial stiffness, and aids in weight management. Smoking cessation reverses many harmful cardiovascular effects of tobacco use, while stress management techniques
such as mindfulness and cognitive-behavioural therapy alleviate the impact of chronic stress. Despite these benefits, socio-economic disparities, cultural influences, and limited healthcare access hinder widespread adoption of these interventions. Public health strategies must create supportive environments through community programs, policy initiatives, and healthcare interventions. This review underscores the need for integrating lifestyle modifications with traditional medical therapies to globally reduce CVD risk and improve public health outcomes.