Pediatric Spinal Cord Myeloid Sarcoma Presenting as Neuroblastoma: Case ReportPediatric Spinal Cord Myeloid Sarcoma Presenting as Neuroblastoma: Case Report - Abstract
A 5-year-old boy, presented a paraparesis and was referred for pelvic neuroblastoma based on MRI finding. The BMA performed in this context revealed an AML M2 with t(8;21) confirmed. The diagnosis of Myeloid sarcoma was confirmed by the histological study of the mass biopsy. The treatment initiated urgently as neuroblastoma was switched to AML protocol. The complete remission was achieved after induction 1 but the patient died from sepsis after consolidation 3.
In conclusion, MS should be considered as diagnosis in children presenting with motor impairment and spinal mass. The diagnosis can be confirmed by BMA but if the bone marrow is not involved the histological and immunohistochemistry studies are mandatory using the adequate markers. Complete remission can be achieved using chemotherapy and steroids with a good prognosis. In Morocco it is necessary to improve supportive care as well as survival in patients with leukemia.