Presence of both Complex Partial Seizures and AtrioVentricular Block - Abstract
Cases in which epilepsy and atrio-ventricular (AV) block coexist are unusual. A 31-year-old man presented with syncope. Holter ECG showed the second-degree AV block and the longest cardiac pause was 6.3 seconds. Even after receiving pacemaker, he repeated consciousness cloudiness. Electroencephalogram revealed spike and waves on the left temporal region, suggesting complicated with complex partial seizure. There was no pathogenic mutation in KCNA1 encoding Kv1.1 potassiume channel of which deficient mice displayed both epilepsy and AV block. Epileptic discharge in the left temporal region could result in bradycardia and sometimes it might be a cause of sudden unexpected death in epilepsy. Neurologists and cardiologists should pay attention to this rare disorder.