Uncharted Pathways: A Rare Case of Bony and Soft Tissue Metastasis from Cervical Carcinoma - Abstract
Background: The most frequent tumors of the spine are metastases. However, we present a particular case characterized by an atypical primary origin resulting in secondary lesions in both the spinal column and adjacent soft tissues - specifically, squamous cell carcinoma of the cervix. Methods: We described a case of a female patient diagnosed with infiltrating Grade 3 squamous cell carcinoma of the cervix in November 2020 underwent a series of treatments, including neoadjuvant radiochemotherapy and then surgery. The patient was monitored until the identification of a bone lesion in the right 10th rib in November 2021, prompting targeted stereotactic radiotherapy. Subsequent evaluations revealed evolving lesions in the thoracic spine and adjacent soft tissues. Results: Despite various investigative procedures and treatments, including chemotherapy and surgical interventions, the patient’s condition deteriorated, with the appearance of extensive metastases in unconventional sites, leading to a challenging diagnostic and therapeutic management pathway. Conclusion: This case exhibits an aberrant metastatic pattern rarely documented in literature, necessitating a comprehensive understanding of such occurrences for enhanced clinical approaches and improved outcomes in similar pathologies.