Prescription Opioid Abuse in the US: The Perfect Storm with No Proven Strategies to Mitigate the Escalating Problem - Abstract
Over the past two decades, the popularity of chronic opioid
therapy (COT) for non-malignant pain has exploded. Presently,
hydrocodone is the number one prescribed medication in the US.
The adaptation of this therapy has become widespread despite
the lack of clinical evidence for long-term safety and efficacy.