Prevalence of Cavum Septum Pellucidum in Alcohol Dependent Patients: A Comparative CT Study - Abstract
Presence of abnormal cavum septum pellucidum (CSP) in patients of schizophrenia has been reported in many studies. CSP has not been reported in patients of Alcohol dependent syndrome (ADS), though less brain weight and volume specially of white matter has been found in neuropathological studies. We selected the CT scans, done in the year 2012 and 2013 of male patients of alcohol dependence syndrome and normal controls, who had been referred for CT scanning to the GirindraShekhar Bose Centre for Neuroimaging and Radiological Sciencesof Central Institute of Psychiatry (C.I.P.), Ranchi, for various reasons. We found 54 CT scans of alcohol dependent male patients and 34 CT scans of normal male controls,who satisfiedthe inclusion and exclusion criteria. We defined any CSP greater than or equal to 6mm in length as abnormal. We found significantly increased prevalence of abnormal CSP in alcohol dependent patients (p= 0.007). Similarly, dimension (length and width of cavum and width of septum) of CSP were significantly larger in patient group than controls.