Quantitative Comparisons of Brain Reward Function during Nicotine and Cocaine Withdrawal - Abstract
Considerable attention has been given to the apparent similarities between nicotine’s effects and those of cocaine and other addictive drugs on brain reward systems. These apparent similarities ignore important quantitative differences. Indeed, the effects of nicotine on brain reward systems has been shown consistently to be significantly weaker than the effects produced by prototypic addictive drugs such as cocaine.