Role of Thyroid Hormone in Adipocyte Physiology and Metabolism - Abstract
Adipose tissue composed predominantly of adipocytes (differentiated fat cells)
serves as a lipid storage and endocrine organ. It plays a major role in lipid metabolism
and glucose homeostasis. Thyroid hormones have been known for years to play a
significant role in energy expenditure and adaptive thermogenesis via the brown
adipose tissue, while its role in white adipose tissue has been less investigated. In
this review we will elucidate what is known so far on the role of thyroid hormone in
regulating metabolism and energy homeostasis in both white and brown adipocytes.