Background: Chronic Kidney Diseases (CKD) is a progressive, irreversible loss of kidney function with great debilitations to the patient and the cost of health care for individuals, their families and a countries overall healthcare cost. The prevention and management of CKD involves the control of conditions that causes or aggravate the disease; prominent among such conditions are hypertension and diabetes. The burden of CKD is unknown in the Gambia and more so among those that are more likely to develop the disease, hence this aim of the study is to determine the burden of CKD among hypertensive and diabetic patients in the Gambia. Materials and Methods: This was a retrospective study of hypertensive and diabetic patients, who have had more than 3months of follow up at the EFSTH Banjul, the Gambia. Those included had done a renal function test and hence eGFR in the period under review. CKD was defined as eGFR < 60 ml/L/1.73M2. Results: The average age of participants was 59 years. The burden of CKD was 27.1%. Majority 45.8% of participants had both HTN and DM; 41% had only HTN and 13% had only DM. Controlled rates of systolic HTN and DM were 36.1% and 22.4% respectively. CKD was associated with the presence of HTN or DM. Conclusion: More than 1 in 4 DM or HTN patient have renal impairment. CKD is associated with chronic medical conditions (HTN and DM).