Diagnostic Efficacy of IgG ELISA in Hydatid Disease: A Retrospective Study
- 1. Department of Microbiology, Sher-i-Kashmir Institute of Medical Sciences, Deemed University, India
Abstract
Most serodiagnostic techniques have been evaluated for diagnosis of cystic hydatid disease caused by Echinococcus granulosus. Each, to varying degrees, has been shown to give false results, with considerable variation between laboratories. The comparative retrospective study was done concerning the sensitivity of the different commercially available IgG ELISA kits based on previous laboratory records of 55 patients diagnosed as hydatid disease either intraoperatively or post operative histopathology with different cyst locations. In house ELISA, DRG IgG kit, Nova Lisa kit and Ridascreen IgG kit were studied. Specific IgG ELISA AgB (antigen B-rich fraction) was the most sensitive test (100%) and the least sensitive tests were the In House ELISA (75%), DRG (75%), Nova Lisa (66.66%), these results coincide basically with the findings of most researchers.