This article is the closing of a series of three originally aimed at the identification, localization, imprinting/downloading, and behavior-ruling of the mind. Tissue cell membrane fatty acids shape a molecular grid wherein informions (tytes1 ) are in a transient ROM-type thermodynamic state. The latter is a program dictating behavior. Red blood cells allow for transport and selection / exchange of informions between peripheral tissues, the heart RAM-type Boolean gates (Homo sapiens) and the brain CPU-type neurons (Homo modestis). Cell membrane extensions (organelles and endoplasmic reticulum) from the cell surface to the nucleus account for the phenotype / genotype interface, allowing for environmental informions to access the genes and guide gene expression (genomics) and evolution (genetics). It becomes evident that the natural / cultural selection of species dear to Darwin is correct to the extent that it derives from that very same selection but of informions dear to Lamarck. Information – the mind – was first and will be last. The body follows with bottlenecks / dead-ends along the way leading to evolutionary leaps and jumps. Homo sapiens – “the poor of spirit” – is facing that reality as we speak. It is becoming a problem, environmentally and socially. Humility and fierce resolve, ie Leadership, are Homo modestis assets to keep climbing the Ladder.

De Meester F (2020) The Mind is a Transient Mathematical Matrix Imprint at Cell Membrane Fatty Acids Level. Ann Psychiatry Ment Health 8(1): 1144.

•    Mind
•    Matrix
•    Cell membrane fatty acids

The two previous articles entitled “Od Ciala (Columbus) do Umyslu (Copernicus) Koncepcje. Identyfikowanie I Lokalizowanie Umyslu”, Psychologia w Praktyce 1/2018(#7), 9-15, and “Psychologia z perspektywy fizyki kwantowej – Medycyjna Jutra”, Psychologia w Praktyce 1/2019(#13), 11-17 (www. psychologiawpraktyce.pl),

(i) established a basis for the elaboration of the basic principles of biological Information Technology (bIT), ie consciousness & mind at cell membrane level, and their ruling of behavior and evolution of all life species on Earth, and (ii) extended on the evolving field of Psychology & Energy Medicine, ie Psychophysics, as mind-keys to body-health promotion & disease prevention/cure.

1 Here defined as the allylic three double bond π-electronic spin configurations (-1,0,+1).

Here, we show how Life has been evolving – naturally then culturally – as self- assembling Instruction or Program – the Mind – in a fractal manner leading to the Evolution of Species – as a result. Addressing the Mind is The way forward for Humanity to keep progressing. We all – each and all of us – live in our own time/space reality.

Leadership has to do with addressing those complex multi-faceted personal realities, through inspiration / consolidation rather than hindrance / procrastination. AI (Artificial Intelligence) is nothing less than the evolving HI (Human Intelligence), potentially. It is not granted though. It is a Responsibility. Beware of Homo sapiens’ remnant / resilient / rampant selfish genes...

As Homo sapiens is in ever greater need to move to the next evolutionary level, the focus on the body that has prevailed from some time until now must be forced a drift away towards the mind. Humans do differentiate themselves from other life species on Earth in that latter respect, only. Biological life started with a cell which – throughout Evolution towards ever complex system – evolved to an egg. The chicken-egg tandem is and remains a model of choice to help understand how body and mind did synergize to help Evolution refine its path. A chicken egg is a container within which all is needed to turn a genetic information into a new life. It can then be inferred that an egg does contain pre-formed body and mind. Blood vessels are first to appear around the yolk of the egg upon embryogenesis, well before any respiratory system are eventually put into place and function. Interestingly enough, red blood cells in mammals do not carry genetic information anymore. Mind appears first in life development and reproduction. Memes come first, not genes. Time/space information is essential to any and all egg cell-based reproduction system, and - from pure observation and inferences - cell membrane fatty acids (phospholipids) can be tentatively pinpointed to as the substrate of the mind. The allylic double bond of unsaturated fatty acids is a unique transistor-like electronic set-up which appears to have all the necessary characteristics and properties for allowing time/space and environmental/societal information (electronic spins or informions) to transcribe and translate into biological instructions. It is the latter which then guides the genetically controlled assemblage of the egg constituents (protein, lipid, carbohydrate) into a life system. Back to the chicken egg then, one sees that the body part is concentrated in the white (albumen) whereas the mind counterpart is located in the yolk (vitellus), and the embryo at the interface (disc / blastoderm). Egg yolk lecithin - the preformed chicken cell membranes/mind substrate - does not differ substantially from any other animal-type egg lecithin, including humans’. It is a highly conserved defined mixture of phospholipids, cholesterol, xanthophylls and micro-nutrients, similar to that circulating in the human body as red blood cells, thereby transporting time/space & environmental/ societal information - the mind - throughout the organism and which – in fine – determines behavior, the phenotype. Given the current - yet observational - evidence in favor of the mind making a difference at time / space and environmental / societal levels between humans and other animal species - including the evolutionary ancestor Homo sapiens - it becomes a must for scientists to attempt at focusing their best attention on the evolutionary selected substrate of the mind, ie red blood cell membrane lipids, and their constituents, with a particular attention to the evolutionary selected allylic double bond.

Cell membranes spontaneously fold into biological matrices which – in turn – function as mathematical matrices for isothermal data (informions or tytes) recording / transmitting at the body self-regulated temperature. At that specific temperature, cell membranes are fluid and all would be moving / translating fast in a Brownian like manner unless a complex network of actin / spectrin filaments wouldn’t keep a relative degree of compression and order between the two by-layers, which in turn allows for biological information technology (bIT) to leave significance to statistically relevant – retained - complex information (Figure 1).

Addressing biological information has to do with/within species-specific antigenic patterns whereas processing/ communicating biological tytes of information relies on contracting actin filaments allowing for spin-tunneling / resonance between internal and external cell membrane leaflets.

Thai language has its own way of translating “understand” into “get into the heart” to express the notion that something is duly understood when it is retained as an “emotion” or, in software terms, a Boolean gate associated with something which is already known / imprinted4 . As a corollary then, one can describe the brain as a cognitive tool (CPU) allowing for new information to find their way to the heart (RAM) or to find their way out. RBCs clean up / regenerate every 2-3 months rendering the process dynamics / self-regenerating. Either a new information is successfully penetrating the heart black box deep memory chips within that interval of time or is eventually lost until the next opportunity to get across. Depression and associated absence of emotion render the learning process static and promote its counterpart, ie creativity (Figure 2).

Here (https://www.youtube.com/watch?v=Ie2j7GpC4JU) is an illustration of what it takes at physiological level to translate environmental information (memes) into elementary tytes of information (informions), which then become recordable into incell-membrane matrices, the latter being grids of aligned allylic double bonds of their characteristic fatty acids, mainly LA, AA, EPA & DHA.

Here (https://www.youtube.com/watch?v=Ie2j7GpC4JU) is an illustration of what it takes at physiological level to translate environmental information (memes) into elementary tytes of information (informions), which then become recordable into in-cell-membrane matrices, the latter being grids of aligned allylic double bonds of their characteristic fatty acids, mainly LA, AA, EPA & DHA.

It is important to realize that the brain can – yet, does not need to – be in body- contact with the mind. Here, it is important to realize the change in perspective. A neuroscientist instrumenting the latest “brain neuroimaging” clinical diagnostic technology on the market – to take that example only – is an illustration of how the “machine” is learning about Homo sapiens, not the other way around. The pace is getting faster with mobile communication & network. Brain & mind/body are dissociated. The brain does not need a mind/body, per se. This is where spiritualism finds its destiny, ie Nirvana, the very last station of Homo sapiens on its way to extinction. As another philosopher once said, “Happiness is the most single incentive to Mediocrity”. A good live example is given by 

2 https://chem.libretexts.org/Courses/University_of_ Kentucky/UK%3A_CHE_103_- _ C h e m i s t r y _ f o r _ A l l i e d _ H e a l t h _ ( S o u l t ) / C h a p t e r s / Chapter_14%3A_Biological_Molecules/14.3%3A_Pho spholipids_ in_Cell_Membranes & http://medcell.med.yale.edu/lectures/ introduction_cell_membrane.php.

3 Time x space or mind (information).

4 “Tell me and I forget; Teach me and I may remember; Involved me and I learn”. Benjamin Franklin.

“Jokgu The Chicken Plays The Piano!” (https://www.youtube. com/watch?v=MzIQWUlH0Bk) where obviously mind/body and brain are located in distinguished live objects. The brain/CPU is the cognitive tool needed to dynamically process informions (the kinetic partner) whereas the body is the carrier of informions, processed or not – set as a mind/body program (the thermodynamic partner). The brain-mind/body segregation is evidenced around the globe and all along the history of Humanity – Kalyuga (https://en.wikipedia.org/wiki/Kali_Yuga), if only with the cultural aspects of it. In modern time, it becomes ever more evident that the brain should / will be centralized with humans behaving ever more like body-mind imprinted cobots5 , for a while...

Cell membrane fatty acids are of two sorts, ie those which are unsaturated with their characteristic allylic double bonds arranged one after the other in a “cis” conformation and those which are saturated and which essentially play the role of an insulator. As depicted in the picture below, the unsaturated fatty acids can be encoded in a linear manner and thereby represent systems of linear mathematical equations. Once organized in cell membrane grids as per the above illustrations, they fold up into physico-chemical matrices where informions can follow the logic of matrix algebra and – in turn – deliver the logic or illogic information where/when it is needed (Figure 4 and 5).

Fact is that the current understanding of non-communicable diseases (NCD) and/or chronic degenerative diseases (CDD) is essentially based on the competition between two families of tissue inflammatory mediators of the omega-6 and omega-3 families, ie an almost exclusive Newtonian Homo sapiens-type body approach.

However, looking from a refreshing time structure-based cell membrane fatty acids perspective, one realizes that the mind approach, ie the interaction of time/space environment with cell membranes fatty acids, may be just as relevant yet is so far ignored. It is no surprise that “lunatism” remains a kind of un-explained medical condition of modern times when one focuses only on the body Newtonian-type aspect of life. Yet, it illustrates and represents a unique opportunity to learn about time/space 

→ cell membrane fatty acids → genes interactions, ie cosmo-genetics/genomics (Figure 6).

Matrices are a powerful computing tool used in multiple aspects of mathematics for their most single properties is of being able to represent any complex physico- chemical systems by a set of as many linear mathematical equations as needed to fully represent them. It is interesting to note that mathematical matrices are Nature’s evolutionary selected method of recording, processing and transmitting Life information. In the field of mathematics, the concept of matrices evolved from a need to obtain compact and simple methods of solving system of linear equations.

Matrices basically are representations of coefficients describing systems of linear equations. Once those coefficients are known and imprinted, they can spontaneously serve as a basis for complex computing such as those developed in electronic spreadsheet programs for personal computer, which in turn are used in different areas of real life business and science like budgeting, sales projection, cost estimation, analyzing the results of an experiment etc. Also, many physical operations such as magnification, rotation and reflection through a plane can be represented mathematically by matrices. Matrices are also used in cryptography (https://en.wikipedia.org/wiki/Cryptography),

5 Read „colaborative robots“.

which is exactly what memes need as recording / expression vehicles. This mathematical tool is not only used in certain branches of sciences, but also in genetics, economics, sociology, modern psychology and industrial management. (http://ncert. nic.in/ncerts/l/lemh103.pdf).

But, most importantly, a matrix does physically contains the solution to the problem it apparently raises with no need for computing. That is the way Natural Selection has gone through – in a fractal manner – for sorting out informions from the origin of the Universe to the inception of Life on Earth. Simply, because there was no computer / designer around… The evolving selfconscious Homo modestis may now decide otherwise, indeed. Determinants are enough information for solving linear equations, eg finding quantities in a chemical solution (chemistry), study of stock market trends, optimization of profit and minimization of loss (economics), etc, but even more importantly at physiological level, they allow for speedy linear transformation, eg change area or volume, change variables in integrals, working out selection processes (incl epi-genetics), – at none energy cost - leaving the brain at rest with a mere sorting activity/work (https:// mathinsight.org/determinant_matrix), ie the gut- feeling. As shown by Cramer’s rule, a nonhomogeneous system of linear equations has a unique solution if the determinant of the system’s matrix is nonzero (i.e., the matrix is nonsingular) (http:// mathworld.wolfram.com/Determinant.html) (Figure 7,8,9,10).

Such matrix-type representation of the reality one lives in allows for a very high degree of freedom in the way one perceives/represents things and most probably also explains the evolutionary origin of the brain’s characteristic neuroplasticity. A similar object, sound, odor, fact may be analyzed differently by two individuals in a similar environment depending on their respective imprinted RAM-type Boolean gates and spontaneous mind-derived linear transformation accessing the cognitive brain. It is therefore no surprise that misperceptions/-understandings are so common in inter-personal communication; in fact, they are the essence of biological – as opposed to in-silico – communication. The secret of successful biological communication is in finding a common confinement or time/space, usually referred to as “common/non-cognitive mind” (heart RAM Boolean gates) or culture. As a corollary, one may also envision that Humanity will not spare a melting phase of cultures/civilizations on its way to progress. 432Hz music therapy may help a long way here in tuning environmentally/socially/historically diverting cultures into a transient common vibrational time/space, thereby allowing for progress at their interfaces.

Blood transfusion is a classical medical / clinical practice considered safe when based on careful blood typing and cross-matching. A blood type is defined on the presence (types A, B, AB) or absence (type O) of inherited antigenic substances (A & B antigens) on the surface of red blood cells (RBCs); a 3rd antigen (Rh factor) can be present (Rh+) or absent (Rh-), which is total ends up producing 8 different common blood types among human populations. In a blood transfusion, a patient must receive a blood type compatible with his/her own blood type. If the blood type are not compatible, RBCs will clump together, making clots that can block blood vessels and cause death. In an emergency, type O blood can be given because it is most likely to be accepted by all blood types. Legends have it that blood type tells about diet (preference / compatibility) and personality (temperament / compatibility) traits (Table 1).

Leadership remains wanting at this critical point of evolutionary transition between the self-centered Homo sapiens and the humanity-centered Homo modestis.

Leadership is about protecting people from themselves, preventively. Leadership does not expect a thank note – even less a bonus – in return. It is about memetics, not genetics. Leadership is Love. It is all about giving away to the most single moral person, ie Humanity. It is no investment. It is painful to the Homo sapiens deep inside us. It literally kills it. Yet, recognizing a mistake is less about losing a war than it is about winning a battle. Homo sapiens is resilient. Defeating it is what takes us up. As Oscar Wilde put it: “Some create happiness wherever they go. Some others whenever they go”. I will relay here, relying on my peers to outperform me in each and all aspects (Figure 11).

As Humans are consciously instrumental in stepping up the evolutionary scale – a premiere throughout Evolution – a number of debates may well be helpful / necessary in attempting to segregate gut-feeling (Homo sapiens) from cognition (Homo modestis) when addressing existential questions. Here are a few ideas to eventually develop along the process: 

- Are children at best with their genetic programmers if Humanity is about memetic programming?

• Would genetic programming not be ideally carried out in a jungle-type free-roaming environment?

• Would memetic programming not be ideally carried out in a humanity-type encoded environment?

- Are the stronger the more dependent, the weaker the more independent?

• What makes a Leader?

• What makes a Mercenary?

- Humanity is one single Moral Person?

• What are divisions for? One side enjoys, one side suffers?

• Happiness is the most single dividend to mediocrity?

- Socialism is the future of Capitalism & Communism?

• Is Socialism ahead of its time awaiting for Homo modestis / Humanism?

• Is Capitalism Homo sapiens’ selfish gut genes expression?

- Does the brain spontaneously segregate from the mind-body as cultural evolution keeps pressure on selection?

• Is Homo sapiens facing an evolutionary dead-end?

• Is Nirvana the last station on the way to Homo sapiens extinction?

- One settles one’s accounts with Life before dying?

• Life is not a gift, it is earned?

• Life is only a trap, ie a fight to the Death?

- Is Nature “God” and/or “Devil”?

• Should Homo modestis take over Nature and be in control?

• Should Homo modestis be pre-imprinted as a Champion?

Table 1: However, knowing that RBCs carry the mind (memes) to virtually each and all parts of the body, past historical observations/ legends may soon turn into real Science all the way from nutrigenetics / genomics (diet/regimen) to psychomics (psychology / psychiatry) derived phenotypes. In that respect, an interesting initial study could be that of blood transfusions from culturally-deviating types O to types O, A, B, AB, thereby following changes in patient diet preferences & personality temperament.

The OCT 27, 2020 – ICE Krakow Poland – Workshop of the TsimTsoum Institute with running title “How to lead in a World cleared from God? An Investment, Essential & Urgent, for You & Your Community” will not be organized as originally contemplated, for practical reasons, only. This does not change anything to the very fact that Homo sapiens is facing an evolutionary dead-end. No choice, really. Homo modestis is released. You may want to reread/-interpret Darwin & Lamarck from the mind perspective in its stead (Figure 12 and Table 2).

I hope this series of three articles targeting the Mind will help Homo modestis – taking the Lead – on the evolutionary cultural journey. Clearly, cell membrane fatty acids and their allylic double bonds have more to say than one could ever imagine. Time to re-consider diet / tissue fatty acids and, in turn, mathematical matrices.

As for the past two articles on the subject, my gratitude goes to Prof Dr Agnieszka Wilczynska, Lead Editor of “Psychologia w Praktyce” (www.psychologiawpraktyce.pl) & Leader of “Heroic Imagination Project – PL” (www.hip.org.pl), and extends to the Scientific Advisory Boards of the Columbus & TsimTsoum Institutes, respectively chaired by Artemis Simopoulos and Ram B Singh, for their inspiration and discrete/patient guidance all over the years since back sometimes in the 1990s.

My wildest hope is that cell membrane lipids will keep unveiling their mind secret, ie the mathematical secret behind Evolution and, from there, will help upgrading Homo modestis – read Human Intelligence (HI) – through the wise development and use / application of artificial intelligence (AI), at the expense of its evolutionary genetic heritage, ie the old-fashioned Homo sapiens. Respectfully.

Table 2: Table shows Darwin Genetics and Lamarck Epigenetics.

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2. De Meester F. 1st International Workshop of the TsimTsoum Institute. Time Series (not spotcheck) Evidence-based Holistic Approach to Health. Book of Abstracts. 2010: 68.

3. De Meester F, Wilczy?ska A, Singh RB, Wilson DW, Pella D, Fedacko J, et al. The Chronomics Trial: Report of a 3- month pilot study. In: Non-Invasive Methods in Cardiology 2011 (Masaryk University, Faculty of Medicine, Brno, Czech Republic) Symposium Proceedings (Halberg F, Kenner T & Siegelová J, eds). 2011; 141-161.

4. De Meester F, Wilczy?ska A, Singh RB, Wilson DW. Why the TsimTsoum Concept is essential to Human Health? In: Nutraceutics, Biomedical Remedies and Physiotherapeutic Methods for Prevention of Civilization-Related Diseases (Podbielska H & Trziszka T, eds) Biomedical Engineering Acta. 2011; 4: 41-42.

5. De Meester F. From Columbus to TsimTsoum Concepts: A Kyoto-Type Approach. In: Omega-6/3 Fatty Acids: Functions, Sustainable Strategies and Perspectives (Meester F, Watson RR, Zibadi S, eds) Humana Press, Springer Science+Business Media New York. 2013; 397-416.

6. De Meester F. Obesity is a « Communicable” Mind Disease. Approaches to Aging Control. Journal of Spanish Society of Anti-Aging Medicine and Longevity. 2014; 18: 7- 10.

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8. De Meester F. Psychology in Practice. Annals of Psychiatry and Mental Health. 2018; 6: 1135. (http://www.jscimedcentral.com/Psychiatry/ psychiatry-6-1135.pdf).

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13. Halberg F, Cornelissen G, Wilson D, Singh RB, De Meester F, Watanabe Y, et al. Chronobiology and chronomics: detecting and applying the cycles of nature. Biologist (London). 2009; 56: 209-214.

14. Crawford MA, Broadhurst CL, Guest M, Nagar A, Wang Y, Ghebremeskel K, et al. A quantum theory for the irreplaceable role of docosahexaenoic acid in neural cell signalling throughout evolution, Prostaglandins Leukotrienes Essent. Fatty Acids. 2012.

15. Crawford MA. The Global Crisis in Mental Ill-Health.

16. Zimbardo PG. The Psychology of Evil.

17. Wilczynska A. Heroic Imagination Project Poland (Projekt Bohaterskiej Wyobrazni Polska)