Disease Identifying Strategy
- 1. 91 Richland Cres., Canada
Since some diseases, like HIV, can hide from the immune system by changing the structure of the DNA of the cell that it infects, then a strategy to help the immune system identify the disease, rather then kill it, would be the best way to combat the disease. So to explain how scientists should apply this strategy, the following is how to find and identify HIV so the immune system can kill it.
Because scientists have identified the nine genes for HIV, which are gag, pol, env, tat, rev, nef, vif, vpr, vpu, and sometimes a tenth gene tev, they can use a technique, like gene expression, to express those genes within a cell to identify the infected HIV cells. Once those cells are expressed, then scientists just need to infect those expressed HIV cells with another virus that the immune system can kill. Therefore, gene expression flags the HIV cells, which calls on a virus that the immune system can kill to infect that expressed HIV cell, and then when the immune system finds the other virus in the HIV cell, it will kill that cell.
Please note that gene expression might not be the best application to flag and call a virus, nor am I aware if there is scientific technology that can create a killable virus that will only infect expressed cells. However, in my discussion with scientists, it seemed like the strategy was possible, but my discussions never went any further to validate my strategy. This means that if the technology can be worked out, then this strategy will kill HIV infected cells. Also note, that this strategy does not destroy the virus, but rather it destroys the cells that are infected with the virus. Also, if this strategy of identifying cells for the immune system to kill works, it should help with other diseases like cancer.
91 Richland Cres.,Toronto, Ontario
Canada, M9C 4C5
Burrell S (2014) Disease Identifying Strategy. J Immunol Clin Res 2(2): 1018.