AbstractIn the present study, a series of new C3-quinazolinone linked ?-carboline conjugates were synthesized successfully and evaluated as DNA intercalative topo I inhibitors. It was found that most of the compounds showed good cytotoxic activity, in partic.....
AbstractObjective: The study was aimed to assess the isolation method for Actinomycetes, understand the current status of the presence of antibiotics producing Actinomycetes in the soil sample of Hile and Jhapa, and evaluate the different methodology of test.....
AbstractNumerous factors such as environmental, physiological, and genetic factors have a deep association with mast cells. These cells not only govern the immune response but also enhanced the defense mechanism naturally and prepared a host defense system. .....
AbstractDrug–plasma protein interactions have a significant impact on both pharmacokinetics and pharmacodynamics (pharmacological effects). It is thus highly interesting to evaluate this binding during the drug development process. The interaction between .....