Recent Articles
-
August 13, 2021 Opinion ArticleAbstract In the present study, a series of new C3-quinazolinone linked ?-carboline conjugates were synthesized successfully and evaluated as DNA intercalative topo I inhibitors. It was found that most of the compounds showed good cytotoxic activity, in partic.....
-
July 31, 2021 Original ResearchAbstract Objective: The study was aimed to assess the isolation method for Actinomycetes, understand the current status of the presence of antibiotics producing Actinomycetes in the soil sample of Hile and Jhapa, and evaluate the different methodology of test.....
-
April 30, 2021 Short CommunicationAbstract Numerous factors such as environmental, physiological, and genetic factors have a deep association with mast cells. These cells not only govern the immune response but also enhanced the defense mechanism naturally and prepared a host defense system. .....
-
March 20, 2021 Research ArticleAbstract Drug–plasma protein interactions have a significant impact on both pharmacokinetics and pharmacodynamics (pharmacological effects). It is thus highly interesting to evaluate this binding during the drug development process. The interaction between .....
-
May 16, 2020 Research ArticleAbstract Cetiedil Citrate Injection, containing 5 mg/mL cetiedil citrate, sodium chloride, and Water for Injection in Type I glass ampules, having an unadjusted pH of 3.3 to 3.7 was insufficiently stable if stored at controlled room temperature (20º to 25º).....
-
August 30, 2017 Case ReportAbstract Introduction: In the ophthalmologic field is not uncommon to find signs and symptoms derived from systemic pathologies. Such cases demand a comprehensive approach that allows full control of the ophthalmic manifestations that can be as severe as ulce.....
-
August 30, 2017 Research ArticleAbstract Using primary observation setting (includes open field, rota-rod, actometer, visual detection of tremor, convulsions, pyloerrection, Streub’s symptom, salivation, reflexes, ambivalence, vocalization and passivity) we investigated the neurotoxicolog.....
-
August 17, 2017 Case ReportAbstract Traditionally, patients who are considered treatment-resistant, or who present with more severe symptoms, are often considered for clozapine therapy.The combination of clozapine with another SGA, or on FGA, is also commonly utilized for such severe c.....