Volume 11 - Issue 3 Articles
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ArticleDecember 31, 2023 | Pages : 205 - 450Abstract Aminoglycosides discovered 80 years ago are still the drug of choice for combating a range of infections, including those caused by multiple drug-resistant (MDR) strains of bacteria. These bactericidal antibiotics are nephrotoxic and ototoxic and oft.....
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ArticleDecember 23, 2023 | Pages : 205 - 450Abstract According to an estimate, about 6.8 million people die every year as a result of neurological disorders. These disorders arise due to degeneration of nerve cells and disrupt normal brain functions impacting personal and professional behaviour like co.....
Volume 11 - Issue 2 Articles
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ArticleDecember 13, 2023 | Pages : 205 - 450Abstract Numerous cellular processes, including the release of neurotransmitters and the contraction of muscles, are largely triggered and regulated by Ca2+ inflow via Ca2+ permeable ion channels. In addition, Ca2+ influx regulates cellular migration and prol.....
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ArticleOctober 29, 2023 | Pages : 205 - 450Abstract Objectives: The common belief is that egg yolk consumption is associated with hyperlipidemia, but some recent studies have reported that egg consumption may help reduce hypercholesterolemia and obesity, and is not associated with incidences of cardio.....
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ArticleOctober 06, 2023 | Pages : 205 - 450Abstract Tartaric acid was incubated with Eu3+-tetracycline and the sample was analyzed by capillary electrophoresis utilizing post-column laser-induced luminescence detection. The D-isomer was detected at concentrations as low as 5 µM. The L-isomer was not .....
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ArticleSeptember 23, 2023 | Pages : 205 - 450Abstract Background: Human Immunodeficiency Virus (HIV) infection seems to take a lead in terms of notoriety among other viruses apart from Ebola which gained notoriety due to its epidemic in the year 2014 and the current COVID-19 pandemic. Its treatment usin.....
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ArticleAugust 18, 2023 | Pages : 205 - 450Abstract The Main protease (Mpro) is a vital enzyme of COVID-19 and plays an essential role, making it an attractive antiviral drug target. The antibiotic azithromycin was proven to be effective against influenza, remdesivir is a broad-spectrum antiviral agen.....
Volume 11 - Issue 1 Articles
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ArticleAugust 05, 2023 | Pages : 205 - 450Abstract Abstract Tizanidine is a centrally acting imidazoline derivative with a novel mechanism of action, closely resembling clonidine in its structure and pharmacological mechanism. Tizanidine has Federal Drug Agency (FDA) approval for the use of muscle sp.....
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ArticleMarch 31, 2023 | Pages : 205 - 450Abstract Ketamine is a N-methyl-D-aspartate glutamate receptor antagonist that has efficacy against chronic major depression. Its mechanism of action likely depends on changes in glutamate-mediated transmission and plasticity in circuits involved in a wide ra.....
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ArticleFebruary 26, 2023 | Pages : 205 - 450Abstract Achieving an effective antimicrobial concentration of a broad spectrum drug by conventional oral or topical route is limited by the barriers of the eye. Systemic drugs are often underused or exploited for ocular use without rationalizing the penetrat.....
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ArticleFebruary 26, 2023 | Pages : 205 - 450Abstract Background: Citrus jabara is a type of citrus fruit originally grown in Kitayama-Mura in Wakayama, Japan, and is reputed to have anti-allergic properties. In this study, we tested whether citrus jabara juice inhibits inflammatory mediators in a mouse.....
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