Recent Articles
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September 25, 2025 Research ArticleAbstract Despite governmental regulations on the use of anti-malarial, antibiotic, and analgesic medications, reports indicate a rise in their misuse. This study evaluated the effects of artemether-lumefantrine (AL), ciprofloxacin (CPX), and diclofenac (DF.....
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August 30, 2025 Review Article
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June 06, 2025 Research ArticleAbstract Beta-2-microglobulin (B2MG), has been reported as a biomarker for the fetal renal function development, including the maturation of the tubular reabsorption mechanisms. The aim of this work was to collate and integrate data from different clinical .....
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June 06, 2025 Review ArticleAbstract It is generally accepted that formaldehyde (FA) is a toxic substance. It is formed in various demethylation and transmethylation reactions. And there is an intracellular system for its detoxification. Meanwhile, its effect on the cell causes a diffe.....
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April 18, 2025 Research ArticleAbstract Purpose: This study was conducted to further evaluate and improve antithrombotic stewardship efforts and decrease perceived overutilization of FXai levels in the emergency department at our institution. Summary: A retrospective chart review was comp.....
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March 13, 2025 Research ArticleAbstract The enzyme reaction mechanisms related to guanidino compounds that are uremic toxins were analyzed using a computational chemical method (in silico analysis). The target enzymes for analyzing guanidino compound metabolism were Glycineamidino transfer.....
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November 22, 2024 Letter to the EditorAbstract Theophylline is a phosphodiesterase inhibitor used in the treatment of asthma, has a narrow therapeutic range and can cause cardiac, metabolic and neurological disorders at toxic doses. Clinical signs of poisoning are: nausea, vomiting, tachycardi.....
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September 20, 2024 Research ArticleAbstract Therapeutic drug monitoring (TDM) studies are generally focused on keeping chronic drug exposure to minimal effective blood levels to better control compliance and to avoid side effects. The usefulness of TDM applied to new generation antipsychotics .....
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September 20, 2024 Research ArticleAbstract Cisplatin is a platinum-based chemotherapeutic that causes acute kidney injury in over 30% of patients. The aim of this study was to develop a population pharmacokinetic/toxicodynamic (PKTD) model of cisplatin-induced kidney injury that incorporates .....
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August 30, 2024 Case ReportAbstract Microplastics becomes an important threat to environment and to humans due to negative impacts on health. Sunlight is known to be the natural energy source that degrades plastic waste at a very slow rate. Based on sunlight, the photocatalytic degrada.....
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May 09, 2024 Case ReportAbstract Our case report describes the successful management of a rare case of massive dabigatran overdose using haemodialysis. There is limited literature and guidelines available to date about the toxicity of dabigatran, monitoring of anticoagulation effe.....
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February 16, 2024 Review ArticleAbstract Hepatitis is a viral infection primarily affecting the liver, causing inflammation and potentially leading to liver damage or failure. It can be caused by different hepatitis viruses, with symptoms ranging from mild to severe and can be acute or ch.....