Recent Articles
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December 23, 2022 Original ResearchAbstract Background: The Integrated Management of non-communicable diseases (NCD) in Non-Government Establishments (iMANAGE), a Malaysian-specific program was developed with a structured framework to deliver multi-platform, cross-functional education to healt.....
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August 02, 2014 Research ArticleAbstract Fostering collaborations across multiple disciplines within and across institutional boundaries is becoming increasingly important with the growing emphasis on translational research. As a result, Research Networking Systems that facilitate discovery.....
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August 02, 2014 CommentaryAbstract The ability to clearly set expectations is an important leadership characteristic. However it is very common for individuals heading up research laboratories or scientific collaborations to struggle with, or not identify the advantages of, explicitly.....
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August 02, 2014 Review ArticleAbstract An increasing focus of public and private funders of medical research is to promote collaborative research teams that translate research findings into community health improvement. Unique collaborative translational research teams are developed to me.....
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August 02, 2014 Short CommunicationAbstract Science is increasingly being carried out in large cross-disciplinary research teams. However, currently little empirical research focused on understanding the outcomes and added-value associated with this type of research approach exists. This study.....
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August 02, 2014 Review ArticleAbstract Strategies for constructing and maintaining cross-disciplinary teams are in their infancy. We outline strategies to support one form, transdisciplinary research, in a major initiative of the National Cancer Institute, the Transdisciplinary Research i.....
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August 02, 2014 Review ArticleAbstract Translational medical teams are transdisciplinary, highly collaborative, and operate within dynamic environments to solve time-sensitive and complex problems. These teams are tasked with turning observations in the laboratory and clinic into effectiv.....
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August 02, 2014 Case ReportAbstract The science-of-team-science is the study of collaborative processes involved in team science initiatives and how these inform and improve team dynamics. Evidence suggests that teams perform more effectively, especially when tackling complex problems,.....
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August 02, 2014 Review ArticleAbstract This paper explores various challenges associated with designing an effective transdisciplinary curriculum and proposes an approach grounded in the concept of constructive alignment and transformational leadership for developing curriculum for clinic.....
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August 02, 2014 Research ArticleAbstract The National Cancer Institute has been a leader in supporting transdisciplinary (TD) team science. From 2005-2010, the NCI supported Transdisciplinary Research on Energetic and Cancer I (TREC I), a center initiative fostering the TD integration of so.....
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August 02, 2014 Review ArticleAbstract The keywords of this special issue–collaboration science and translational medicine–appear frequently in conjunction with two other terms–“Interdisciplinarity” (ID) and “Transdisciplinarity” (TD). Interdisciplinarity is linked with coll.....
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August 02, 2014 Review ArticleAbstract Collaboration is a basic social activity. It exemplifies our uniquely human capacity and creative desires to solve problems using all available resources through shared social goals.
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May 04, 2015 Case ReportAbstract Background: Although the last decades have witnessed more pulmonary embolism (PE) in China, PE in young adults is rare. Here we reported a young man of saddle PE with several lung infiltrations in imaging which was misdiagnosed as pneumonia for thr.....
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August 02, 2014 Review ArticleAbstract Current issues require a team of experts with various backgrounds and expertise, and this has led to an increase in the importance of collaboration within medicine and science. However, a team of such experts does not ensure an expert team. Collab.....
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February 24, 2014 Review ArticleAbstract von Hippel-Lindau (VHL) disease is an autosomal dominant disorder that is associated with germline mutations of VHL tumor suppressor gene, which is located at short arm of chromosome 3. This condition predisposes to the development of various beni.....
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March 20, 2014 Review ArticleAbstract Concern over radiation-induced cancers has increased over the last ten years. A number of spectacular overdoses with medical radiation has alarmed the public and caused a strong reaction in the professional and manufacturing communities. Medical i.....
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March 13, 2014 Review Articlevon Hippel-Lindau Disease Associated Pancreatic Neuroendocrine Tumors – Molecular Genetics and Clinical AspectsStefan Zschiedrich Philipp T. Meyer Ozer Makay Monika Engelhardt Martin K. Walz Laura von Duecker Kurt Werner Schmid Karoly Rácz Hartmut P. H. Neumann Giuseppe Opocher Georges Weryha Frederic Castinetti Ernst von Dobschuetz David Taieb Bahadir M. Güllüoglu Attila Patocs Angelica Malinoc Birke Bausch Xiao-Ping Qi Schu-Ren YangAbstract Pancreatic neuroendocrine tumors (PNETs) occur in about 10% of patients with von Hippel-Lindau disease (VHL). Females are more frequently affected than men. VHL associated PNETs are virtually always endocrine inactive. PNETs are mostly detected in p.....
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March 03, 2014 Research ArticleAbstract Patients with von Hippel-Lindau (VHL) disease develop tumors and cysts in the central nervous system (CNS), retina, adrenal gland, kidney and pancreas. These tumors or cysts always require surgical treatment and cause different degrees of impairment.....
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April 06, 2014 Research ArticleAbstract Purpose: We analyzed the clinicopathological features and prognosis of renal cell carcinoma (RCC) in Japanese patients with von Hippel Lindau (vHL) disease. Patients and methods: The subject was 52 vHL patients with kidney tumors. Clinical, pathol.....
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January 06, 2013 Review ArticleAbstract Hemangioblastomas are a rare form of benign vascular tumors of the CNS. They can occur sporadically or as component of the von Hippel-Lindau (VHL) disease - an autosomal dominant tumor syndrome. The tumors are typically located in the posterior foss.....
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July 09, 2014 Review ArticleAbstract von Hippel-Lindau (VHL) disease is a highly penetrant multiple organ heritable cancer syndrome with a spectrum of benign and malignant tumors. VHL is results from a germline mutation of the VHL tumor suppressor gene (short arm of chromosome 3). VH.....
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December 06, 2013 Research ArticleAbstract von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited syndrome characterized by a predisposition to various neoplastic lesions. To clarify the epidemiology and clinical characteristics of VHL-associated pheochromocytoma (PHEO) in Japa.....
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November 23, 2013 Review ArticleAbstract von Hippel-Lindau tumor suppressor (VHL) protein functions to cause somatic stem cells to differentiate into neurons. Not only VHL protein but also a peptide derived from it shows this capability of eliciting neuronal differentiation by somatic ste.....
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November 23, 2013 EditorialAbstract von Hippel-Lindau (VHL) disease is an autosomal dominant hereditary multicancer syndrome manifesting as central nervous system (CNS) hemangioblastoma, retinal hemangioma, renal cell cancer, pheochromocytoma or pancreatic neuroendocrine tumor [1].
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December 19, 2013 Review ArticleAbstract VHL patients develop tumors in brain, spinal cord, nerve roots, kidney, adrenal gland and extra-adrenal ganglia, pancreas, epididymis and broad ligament. VHL disease produces highly characteristic neuropathologic changes which are presented in thi.....
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December 28, 2013 Review ArticleAbstract von Hippel-Lindau (VHL) disease is caused by a mutation in the VHL gene, resulting in the functional disorder in VHL-encoded protein (pVHL). Recent advances in experimental and clinical studies on VHL gene/protein and VHL disease have provided nov.....