Giant Retroperitoneal Myxoid Liposarcomas, Survival in Chromosomal Fragility
- 1. Department of Surgery, Complutense University, Spain
- 2. Division of Surgery, Hospital Angeles León, Mexico
Abstract
Background: Primary retroperitoneal sarcomas are rare, corresponds 0.1 to 0.2 percent of all malignant lesions in adults and represents 10-15% of all soft tissue sarcomas.
Objective: To describe the survival in two patients with giant retroperitoneal tumor when complete resection is carried out and the association with chromosome 16q breakage observed in karyotype obtained from peripheral blood.
Clinical cases: We report two similar clinical cases of large retroperitoneal myxoid liposarcoma in female patients. Physical examination revealed a globular abdomen due to a large mass in both cases. The diagnostic test were; abdominal X-ray, ultrasound, abdominal computed tomography (CT-scan), pyelography, arteriographyand cavography, CT-scan guided fine needle aspiration biopsy and the peripheral blood was cultured and processed for G and C banding. Any of them did not receive chemotherapy or radiotherapy. Survival time free disease reaches 12 and 19 months
respectively.
Conclusions: Both patients with increased 16q ruptures in peripheral blood and a large retroperitoneal myxoid retroperitoneal liposarcoma resected without chemotherapy and radiotherapy showed a short survival.