A 57-year-old woman presented with a full-thickness macular hole and concomitant rhegmatogenous retinal detachment in the left eye. She underwent 23-gauge pars plana vitrectomy, phacoemulsification and intraocular lens (IOL) implantation. After perfluorocarbon-assisted flattening of the retina and complete removal of the perfluorocarbon, an inverted internal-limiting-membrane (ILM) flap was made to cover the macular hole, followed by 14% C3F8 tamponade. At post-operative week 3, OCT showed complete macular hole closure and a flat retina, but a hypo-reflective micro-droplet was trapped beneath the ILM flap — residual perfluorocarbon (Figure 1).

Figure 1 Post-operative OCT demonstrating a single residual perfluorocarbon liquid droplet (hypo-reflective, white arrow) is trapped beneath the ILM flap.