Recent Articles
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December 13, 2018 Research ArticleAbstract Background and objective: Stenting of long lesions TASC C-D of the superficial femoral and/or popliteal artery (SFPA)in patients with critical limb ischemia (CLI) is associated with a restenosis rate of around 50% at one year. The aim of the present .....
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May 02, 2018 Case ReportAbstract A 63-year-old woman was admitted for influenza A infection and elevated cardiac troponin I without dynamic changes on the ECG. She had recently undergone coronary angiography which had shown normal coronary vessels. Her troponin I levels were persist.....
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April 05, 2018 Review ArticleAbstract Aging is the most profound risk factor for many non-communicable diseases and in itself confers a greater risk for cardiovascular disease than the traditional risk factors such as lipid levels, smoking, diabetes, hypertension and sedentary lifestyl.....
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November 13, 2017 Commentary
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October 06, 2017 Short CommunicationAbstract Critical limb ischemia (CLI) is the advanced presentation of peripheral arterial disease (PAD), characterized by persistent pain at rest and/or necrosis for more than two weeks. Endothelial dysfunction (ED) is considered a constant process during vas.....
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June 16, 2017 Review ArticleAbstract Capillaroscopy is a non-invasive method for the observation of capillary microvasculature. In recent years, it has gained recognition in the field of diseases that affect microcirculation, especially in rheumatic diseases. However, studies published .....
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May 30, 2017 Review ArticleAbstract Atherosclerosis is a progressive disease that involves damage to the endothelium of the arteries, as well as the formation of atheroma plaques. The risk factors for atherosclerosis are unknown. However, high levels of LDL (Low Density Lipoprotein) a.....
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May 25, 2017 Review ArticleAbstract The prevalence of obesity is increasing worldwide, and obesity is a known risk factor for venous thromboembolism (VTE) and the development of atrial fibrillation. While warfarin remains the most commonly prescribed oral anticoagulant worldwide, dire.....
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May 23, 2017 Mini ReviewAbstract Postoperative atrial fibrillation (POAF) following cardiac surgery represents a common, potentially morbid, and often misunderstood complication. Patients who develop POAF incur an increased cost of care, a prolonged hospital stay, and are at a hig.....
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May 13, 2017 Mini ReviewAbstract Adipose tissue was for a long time seen as just a way of storing excess of energy. However, in the second half of the past century many studies began to show that adipose tissue is in fact an endocrine organ with autocrine and paracrine functions due.....
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April 21, 2017 Case ReportAbstract Rupture of a PTMC (Percutaneous Transluminal Mitral Commisurotomy) balloon during the procedure with complications like embolism have been described in literature. Most of these complications used to occur with reused and sterilized balloons and th.....
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April 20, 2017 Review ArticleAbstract The introduction of direct oral anticoagulants (DOACs) represents an epochal advance for stroke and arterial systemic embolism prevention in patients with non-valvular atrial fibrillation (NVAF), nevertheless their employment is no longer so easy to .....
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March 21, 2017 Research ArticleAbstract Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the protozoan Trypanosoma cruzi. T. cruzi targets adipose tissue, which serves as a reservoir of this parasite. T. cruzi infection of adipose tissue i.....
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March 14, 2017 Short CommunicationAbstract High levels of plasma triglycerides (TG) are a risk factor for cardiovascular diseases often associated with abnormalities in other lipids or lipoproteins. The objective has been to determine the prevalence and factors associated with hypertriglyceri.....
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March 07, 2017 Case ReportAbstract In Brazil, the Chagas disease is among the parasitic diseases which takes part in screening pre-transplant on the donor and recipient, because in case of positive results it is indicated the anti-parasitical therapy. The immunosuppressive therapy in .....
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March 07, 2017 Review ArticleAbstract This is a review of most common congenital aortic abnormalities illustrated by clinical cases with typical CT and MRI findings.
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February 13, 2017 Review ArticleAbstract Hypertriglyceridemia (HTG) is an independent factor of atherosclerotic cardiovascular disease and a hallmark of many metabolic disorders. However, the molecular etiology of HTG is still largely unknown. In mice, severe HTG may be induced by expressio.....
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February 11, 2017 Research ArticleAbstract Backgrounds: Besides comprising high-density lipoprotein (HDL), apolipoprotein A1 (ApoA1) itself acts as an anti-atherogenic substance but its supplying routes and localization in the human coronary artery wall is poorly understood. The present study.....
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February 04, 2017 Review ArticleAbstract This is a pictorial essay reviewing typical computed tomography findings of acute aortic syndrome, traumatic aortic injury, aortitis and some common diagnostic pitfalls.
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January 28, 2017 Case ReportAbstract New RBBB or bifascicular block development in acute anterior myocardial infarction (AnMI) is a poor prognostic sign [1]. This is because of the left anterior descending artery (LAD) occlusion before or at the level of the first large septal branch (.....
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January 16, 2017 Case ReportAbstract Fibromuscular Dysplasia (FMD) is an arteriopathy that can affect any vascular territory, though most often affects the renal and carotid arterial beds. Symptoms are consistent with the vascular bed affected and are often attributed to other condition.....
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January 05, 2017 Short CommunicationAbstract Carotid intima media thickness (IMT) has been widely utilized as an indicator of atherosclerosis in epidemiological, observational, and interventional clinical studies. It has been applied as an outcome variable in clinical investigation, and it ha.....
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January 04, 2017 Review ArticleAbstract Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in basic to clinical and surgical approach, treatment and drug therapy are required. Health and Medicine emphasizes holistic approaches to.....
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December 08, 2016 Review ArticleAbstract The Endoglin (ENG) gene encodes a major glycoprotein that belongs to the TGF? superfamily. In humans, mutations in the ENG gene are associated with an autosomal dominant disease, hereditary hemorrhagic telangiectasia (HHT). HHT patients have a hig.....
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November 13, 2016 Research ArticleAbstract The microregion of Uberaba, in Minas Gerais state, Brazil, is an important center for breeding, genetic development, and cattle related business. Since 2011 outbreaks of bovine trypanosomiasis have been noticed in the region, leading to high mortalit.....
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November 03, 2016 Review ArticleAbstract Chronic and long-lasting inflammation is the beginning of the endothelial dysfunction process and atherosclerosis. Thus, C-reactive protein (CRP) initially described as an acute phase protein is a marker of cardiovascular disease but not so early on .....
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November 02, 2016 Research ArticleAbstract The renin-angiotensin system (RAS) has long been known as a regulator of blood pressure and fluid homeostasis. In past several decades, local renin-angiotensin systems have been discovered in various tissues and novel actions of angiotensin II (ANGII.....
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November 01, 2016 Research ArticleAbstract Patients with chagasic megacolon exhibit lesions of the enteric nervous system (ENS), associated with the inflammatory process and, some substances, like neurotrophins, may restrict neuronal destruction levels. The objective of this study was to char.....
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October 23, 2016 Mini ReviewAbstract Statins are a class of drugs which primarily funcion as competitive inhibitors of HMG-CoA reductase. There are numerous studies investigating the effect of statins on cancer patients with contradictory and controversial results. Regarding renal can.....
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September 10, 2016 Review ArticleAbstract Takotsubo cardiomyopathy (TTC) is characterized by transient regional systolic dysfunction of the left ventricle in the absence of angiographic evidence of obstructive coronary artery disease or acute plaque rupture. In most cases of takotsubo car.....
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September 07, 2016 Short Note
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September 03, 2016 Review ArticleAbstract Chagas disease is a protozoonoses caused by Trypanosoma cruzi. After chronification, human infection may present with several clinical manifestations, ranging from asymptomatic disease to severe cardiomyopathy. Currently, it is estimated that abou.....
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September 01, 2016 Review ArticleAbstract Hypercholesterolemia and low-grade inflammation are both basic factors that contribute to the genesis and progression of atherosclerosis. AMP-activated protein kinase (AMPK) is proposed to be a key regulator of cellular and organismal metabolism. .....
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August 24, 2016 Short CommunicationAbstract Acute coronary syndrome (ACS) refers to a spectrum of clinical presentations associated with rupture of an atherosclerotic plaque and partial or complete thrombosis of the infarct - related artery. Aim of the study was to estimate the whole lipid s.....
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August 24, 2016 Clinical Image
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August 09, 2016 Review ArticleAbstract Cardiac Allograft Vasculopathy (CAV) is a serious complication after heart transplantation in adults as well as children and once developed irreversibly compromises the outcome of the recipients. Human leukocyte antigen mismatches, number and dura.....
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June 14, 2016 Research ArticleAbstract Background: The purpose of this study was to investigate the effects of TCF7L2 on T2D in a Tunisian population, in a comparison with African Americans and Caucasians, studied before by Yan et al. Methods: We investigated the association between the .....
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April 28, 2016 Review ArticleAbstract Cardiovascular Disease (CVD) remains a major cause of morbidity and mortality in developed society. Since oxidative stress and inflammation are key players in the etiology of CVD, it is conceivable that natural antioxidants such as carotenoids, exist.....