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  • ISSN: 2334-1831
    Early Online
    Volume 5, Issue 3
    Research Article
    Ramon Silva-Vazquez, Lorenzo Antonio Duran-Melendez, Gerardo Mendez-Zamora, Eduardo Santellano Estrada, Meizhen Xie, Nurhan Turgut Dunford*, and Carla Goad
    Essential oil of oregano is known for its antimicrobial and antioxidant properties. The aim of this study is to investigate the antioxidant capacity of essential oils obtained from 5 different Mexican oregano ecotypes and the fractional distillation of these oils. Total phenolic content of the oil samples was analyzed. Antioxidant activity of the samples were examined by the following assays; Oxygen Radical Absorbance Capacity, 2,2-Diphenyl-1-Picrylhydrazyl, and Oxidative Stability Index (OSI). Chemical composition of the samples was determined by gas chromatography.
    Thymol and carvacrol were the main components in all samples examined in this study. There were significant differences in chemical composition of oils obtained from various Mexican oregano ecotypes. Oregano essential oil fractions with antioxidant capacity similar to or higher than that of the synthetic antioxidant butylated hydroxytoluene were obtained by fractional distillation. This study demonstrated that oregano oil and its fractions can be viable alternatives to the synthetic antioxidants widely used in foods and animal feed.
    Short Communication
    Teresa Cristina dos Santos Leal* and Alaercio Aparecido de Oliveira
    In General, hospitals and clinics use equipment that can generate radioactive waste, i.e. material with radionuclide content inappropriate for the environment and harmful to public health. The overall objective of this study is to highlight the consequences of incorrect handling and disposal of hospital material containing radioactive elements can bring to peoples lives and to stress the need for more studies and public policies for control and dissemination of knowledge between employees and the public to use such services.
    Editorial
    Luna Liang, Chen Huang, and Arthur J. Ragauskas*
    Cellulose is the most abundant terrestrial polymeric material in nature composed of -D-glucopyranose units linked by -(1-4) glycosidic bonds. Due to its characteristics of broad availability, biodegradability, biocompatibility, and renewability, cellulose can be used as sustainable materials for biomedical and industrial applications such as packaging, hygiene, paper, films, membranes, tissue engineering, hydrogels, and aerogels.
    Review Article
    Donatella Delle Cave#, Concetta Paola Ilisso#, Laura Mosca, Martina Pagano, Elisa Martino, Marina Porcelli*, and Giovanna Cacciapuoti
    S-Adenosyl-L-methionine (AdoMet) is a naturally-occurring sulfonium compound found in almost every tissue and fluid in the body that plays a central role in cellular metabolism. AdoMet, indeed, is the link to three key metabolic pathways: polyamine synthesis, transmethylation and transsulfuration. Literature and clinical studies regarding the AdoMet physiologic and physio-pathological roles underline its therapeutic potential to treat alcoholic liver disease, depression and joint pain. In recent years, several new metabolic functions have been assigned to this important and widely occurring sulfonium compound that exerts pleiotropic effects on signal transduction in many and different cell-types. In the last decade a lot of in vitro and in vivo studies highlighted the anti-proliferative, anti-metastatic and pro-apoptotic effects of AdoMet in cancer cells. In this review we summarize the most recent studies focusing on the anticancer effect of AdoMet in breast cancer cells and provide information on the broad spectrum of mechanistic actions underlying the antitumor effect of this physiological sulfonium compound. Our data on the synergistic effects of AdoMet with conventional therapeutic drugs appear to be clinically relevant and disclose a new scenario of intervention in which this natural and safe molecule, alone or in combination with other chemotherapy drugs could be utilized for the development of novel promising therapeutic strategies for the treatment of breast cancer.
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