Recent Articles
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July 10, 2024 Research ArticleAbstract Introduction: In CKD patients, the leading cause of mortality is cardiovascular disease. In most cases, it is related to vascular calcification. Among multiple risk factors for vascular calcification, decline of residual renal function is an import.....
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May 22, 2024 Research ArticleAbstract Chloroquine, an aminoquinoline, which was formerly the first-line drug for the treatment of malaria for many years until it was discouraged due to drug resistance strains of malaria parasite has been re-purposed for the treatment of many infectious, .....
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May 06, 2024 Mini ReviewAbstract Autosomal Dominant Polycystic Kidney Disease (ADPKD) presents a significant burden globally, including in Tunisia. This retrospective study aimed to characterize ADPKD cases in Tunisia, focusing on clinical manifestations, therapeutic interventions, .....
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May 06, 2024 Case ReportAbstract Muscular infarction, though rare, is a notable complication of diabetes mellitus in patients undergoing hemodialysis. Its pathophysiology remains elusive. Herein, we present two cases, one involving a young woman and the other a young man, both man.....
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May 06, 2024 Review ArticleAbstract Clinical nephrology encompasses a broad spectrum of kidney diseases, ranging from acute kidney injury to chronic kidney disease (CKD) and end-stage renal disease (ESRD).
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April 15, 2024 Short CommunicationAbstract Diabetes is the leading cause of end-stage kidney disease (ESKD) worldwide.
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March 15, 2024 Case ReportAbstract The kidneys, like the duodenum and the pancreas, are retroperitoneally located and this makes it hard to detect injury to them. The kidneys can be injured both by blunt and penetrating trauma. A high index of suspicion and mechanism of injury would.....
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May 13, 2023 Research ArticleCombined Immunosuppressive Treatment in Children with Primitive Steroid Resistant Nephrotic SyndromeAbstract Objective: Steroid Resistant Nephrotic Syndrome (SRNS) is a rare condition where 10-20% of children with nephrotic syndrome will not respond to prednisolone therapy. Immunosuppressive therapy with drugs such as Cyclosporine A (CsA), Mycophenolate Mof.....
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April 17, 2023 Case ReportAbstract Background: Patients with membranous nephropathy (MN) may have an associated malignancy, commonly solid tumors. Here we present a case of T-cell acute lymphoblasti leukemia (T-ALL) and concurrent MN; the clinical course indicated there was a causal l.....
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March 19, 2023 Research ArticleAbstract Background: A major challenge for successful renal transplantation is to develop an efficient regulation to prevent allograft rejection. T helper 17 cells (Th17) (pro-inflammatory) and many regulatory T cells (CD4+CD25+; Tregs) (anti-inflammatory) ha.....
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January 20, 2023 Case ReportAbstract Effective therapy for a lupus nephritis flare is still elusive. Topoisomerase I inhibitor irinotecan as add on therapy is shown to have favourable outcome in lupus nephritis but its use in lupus nephritis flare is not reported. Objective: To study t.....
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May 08, 2017 Review ArticleAbstract Background: Autosomal Dominant Polycystic kidney disease (ADPKD) is the most frequent renal hereditary disease, most commonly revealed in adulthood. It is characterized by the development of multiple cysts in the kidney and many other extra-renal man.....